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Iboga Blog
ibogaine
29th April 2019
What You Need to Know About Iboga Therapy
If you’re here, you’ve probably heard about Iboga’s remarkable utility in treating all manner of addictions. You’re curious about how this substance works, and concerned about the risks associated with a psychoactive substance that’s illegal in some countries.
If you’re looking to know more about the fascinating history of Iboga, click here, but if you’d like to learn everything you need to know about Ibogaine’s use in treating addiction, keep reading!
How It Works
Iboga’s powerful addiction treatment properties were discovered by an American named Howard Lotsof. As a 19-year-old addict, Mr. Lotsof experimented with psychedelic substances to treat his addiction and discovered that a single dose of Iboga brought an end to the physical symptoms of heroin withdrawal, and dramatically reduced his cravings for drugs. What did it feel like? In the words of one recovered addict:
"As it starts to take effect I feel an intense wave of energy emanating from the center of my chest that permeates my entire body. This euphoric state also brings me instantaneous relief from the discomfort I was feeling after going without heroin for almost 24 hours.
With my withdrawal symptoms completely gone, I am perplexed by the state of clarity I am in while seeing the most profound stream of visual phenomena. I am also filled with a sense of awe at the potential for a life free of heroin. Emotional memories force me to deal with some of the deep subconscious guilt I have repressed for years.
This powerful state persisted for over 12 hours. After remaining at the clinic for a week I was allowed to return home and over the next six months felt almost no cravings whatsoever."
While scientists are not exactly sure how Iboga works, they know it interacts with sigma receptors and 5-HT2A receptors in the brain. Sigma receptors are “opioid receptors” that are activated by drugs like heroin. Researchers theorize that Iboga lightly stimulates them, helping to ease withdrawal symptoms, much like how a nicotine patch helps smokers treat nicotine withdrawal. 5-HT2A receptors are the ones typically activated by psychedelic drugs, and it’s believed that activating them helps to treat depression, while also disrupting thought patterns, allowing the user freedom to break free from negative thoughts and self-destructive patterns of behaviour.
Iboga has been proven to successfully disrupt addiction for a period of 3-6 months for individuals who habitually use opioids, opiates, and stimulants. It resets the brain to a pre-addiction state, and helps cleanse all traces of drugs from your body. However, it is not a magic bullet for treating addiction, and those who hope to lead healthy lives must put in the work to prepare themselves for a life free from addiction. For those addicted to Benzos and alcohol, Iboga therapy can provide substantial benefits, but it cannot help with the withdrawal process.
Iboga use: the risks
Iboga use is not without its risks. We certainly don’t want to sugar-coat the fact that there have been some deaths associated with iboga therapy. Between 1990 and 2008 a total of 19 deaths were associated with Iboga use, and the rate of death during treatment episodes was 1 in 427 (for comparison, the rate of death in Methadone treatment was 1 in 364). Deaths during treatment have mainly been associated with bradycardia (slowing of the heart), liver problems, seizures, and lethal interactions with other substances. Another thing to consider is that Iboga therapy generally restores addicts to a “novice state”, meaning that following treatment their tolerance for substances is significantly lower than it had been, thus increasing the risk of overdose.
So yes, Iboga therapy carries significant risks. But should these risks stop people from seeking it out? The first thing to bear in mind is the dangerous nature of addiction. In the United States, 115 people die every day from the misuse of opiates and opioids. And overdoses are on the rise, in fact, they increased a full 54% in American cities during 2017, according to government studies. Not to mention the fact that drug users suffer from diseases like HIV and Hepatitis at far greater rates than the general population. Individuals suffering from a substance use disorder are 4 times more likely to die from unnatural causes than the average person.
The dangers of heroin addiction are so horrifying that the risk of using Methadone, a treatment associated with a higher rate of death than Iboga, is considered acceptable by doctors and governments the world over. And when comparing the risks of Iboga and Methadone, it should be noted that many of the deaths associated with Iboga use have occurred when the drug was self-administered and used without any degree of medical supervision. Methadone treatment, in spite of being prescribed and administered by medical professionals, is still more dangerous than Iboga!
Iboga safety
While risks are inherent in any treatment of addiction, many of them can be minimized, or even eliminated by taking proper precautions. With Iboga, the first step is to find out if it is safe for you.
Individuals suffering from heart defects and other heart problems are at the greatest risk. Those with impaired liver or kidney function, some psychological disorders, and epilepsy should probably avoid using Iboga. You can see our inclusion and exclusion criteria here, and while we are firm believers in the efficacy of Iboga therapy, we recognize that it can’t work for everyone.
At Iboga Tree Healing House, we provide you with the safest possible setting for Iboga therapy. Unlike the vast majority of Iboga clinics, we have a medical doctor in-house, rather than on-call or at a nearby hospital. We have a nursing team that is based on a 1:1 nurse per patient ratio. We insist on taking a full medical history prior to treatment, as well as a full set of lab results including a full blood panel, liver function analysis, ECG/EKG and more. We also monitor our patients with an EKG machine during treatment. Furthermore, every member of our medical team is ACLS certified by the American Heart Association.
The safety of our clients is our number one priority, and we feel that by taking every precaution, we can offer Iboga therapy that minimizes the health problems associated with treatment and eliminates the risk of death.
23rd April 2019
Ibogaine: a brief history
Ibogaine has probably come to your attention for the immense promise it has shown in treating addiction. But this fascinating substance has been impacting human societies for thousands of years. As the opioid epidemic grabs international headlines and alternative addiction treatment options move to the forefront of the conversation, let’s take a look at the amazing history of Ibogaine.
Who discovered iboga?
It is widely believed that pygmies from Central Africa first encountered the tabernathe iboga shrub in Gabon and Cameroon. The common-seeming plant yields simple yellow flowers and an almost tasteless sticky orange citrus fruit. But the pygmies came to realize that when the root bark was scraped off, ground into powder and ingested, it had powerful psychedelic properties. The pygmies passed this knowledge along to others, and thus planted the seeds of the Bwiti spiritual discipline.
Who are the Bwiti?
Bwiti is a Spiritual discipline practiced among the Babongo and Mitsogo people of Gabon, and the Fang people of Gabon and Cameroon. Contemporary adherents believe in a mixture of animism, ancestor worship and Christianity, but Ibogaine is at the core of their rituals and beliefs. According to Wikipedia, the substance is used to “promote radical spiritual growth, to stabilize community and family structure, to meet religious requirements, and to resolve pathological problems.”
When Bwiti shamans consume Ibogaine, they believe that they gain the ability to heal the sick, communicate with the dead, and experience visions of the future. Perhaps most significantly, Iboga is crucial to the initiation rites and coming of age rituals of the Bwiti. According to Daniel Lieberman, an expert on Bwiti culture, “they believe that before initiation the neophyte is nothing. Through the ceremony you become something…a baanzi, one who knows the other world because you have seen it with your own eyes.” According to Lieberman, the Bwiti believe that ibogaine is a “superconscious spiritual entity that guides mankind.” The majority of the Bwiti people consume Iboga as part of their coming of age ritual, and it is a fundamental building block of their culture and community.
How did ibogaine make its way to Europe?
French explorers to Gabon were the first Europeans to encounter Ibogaine, around the year 1900. Ibogaine hydrochloride was first extracted from the shrub in 1901 by a pair of French scientists, and research into the substance’s interactions with the nervous system first began appearing in scientific literature soon thereafter. As the century wore on, more and more research was conducted, before Ibogaine was finally introduced to the French public in 1930. Marketed under the name Lambarene (the name of the town where explorers first discovered it, and also the location of humanitarian Dr. Albert Schweitzer’s famous hospital), Ibogaine was used as a treatment for depression, and a mental and physical stimulant for healthy people at times of great exertion. Lambarene contained 5-8 milligrams of Ibogaine per tablet and was generally prescribed to treat depression, asthenia, convalescence, and some infectious diseases. It was available legally until 1967 when its sale was prohibited.
Studies, Studies and More Studies
Harris Isbell, the pioneering drug researcher and director of research for the National Institute of Mental Health’s Addiction Research Center performed some of the first American studies on Ibogaine in conjunction with the pharmaceutical firm CIBA. They were looking to create an anti-hypertension drug, and through their research became aware of the substance’s anti-addictive properties. However, all records of their research were declared lost, and the drug was determined to lack commercial viability.
American Howard Lotsof was the first to take Ibogaine seriously as a treatment for addiction. At the age of 19 Mr. Lotsof was a heroin addict experimenting with psychedelic substances as a way to treat his addiction. He found that a single dose of Ibogaine had seemingly ended his physical dependence on opiates. After attending college and marrying, he began researching, authoring scholarly papers, and advocating for the use of Ibogaine in addiction treatment. He acquired numerous American patents on “utilizing the ibogaine molecule as an ultra-rapid method for interrupting or attenuating a large spectrum of poly-drug dependency syndromes” between 1985 and 1992. In the late 1980s Lotsof persuaded a Belgian company to manufacture the drug in capsule form, and began a series of clinical trials in the Netherlands. The success of these trials inspired a growth in Ibogaine based treatment throughout Europe and the Americas.
The US government undertook a series of tests on Ibogaine between 1991 and 1995, before funding of the Ibogaine Research Project was abruptly cut. But recent studies conducted in Brazil, New Zealand, and Mexico have shown “that ibogaine may have a significant pharmacological effect on opiate withdrawal” and all participants in the New Zealand study described their Ibogaine experience positively. While most of the Ibogaine studies thus far have been fairly small, they have uniformly found that the substance seems to reduce cravings and physical withdrawal symptoms for individuals dealing with a variety of addictions.
The Future
With America and many other parts of the world in the midst of an epidemic of opioid use and fentanyl-related overdoses (the US Center for Disease Control reports that 91 deaths per day were caused by opioid abuse in 2016), it seems likely that more and more research will be conducted. At Iboga Tree Healing House we are thoroughly convinced that this remarkable natural substance can be used to treat addiction effectively, and we feel confident that research will bear this out. Ibogaine has had a remarkable history, and we feel that it can make all of our futures brighter!
